In 1941, a substance extracted from spinach leaves and named folic acid from the Latin word "folium" for leaf was found to be effective in the treatment of anemia.
Folic acid is the parent compound of a large group of naturally occurring, structurally related compounds collectively known as the folates.
Folic acid is a water-soluble vitamin.
This vitamin is absorbed from the small intestine, carried by the bloodstream and stored in the body, but not in significant amounts. 7 mg are stored in the liver and other tissues but they can supply the deficiency only for a few months. The body uses what it needs and excretes what is in extra through urine.
Roles
Folic acid participates in several important metabolic processes in the body.
It is essential for the normal growth and maintenance of all cells because it acts as a coenzyme for normal DNA and RNA synthesis.
Folate is vital for the reproduction of the cells within the fetus. A deficiency affects normal cell division and protein synthesis, especially impairing growth.
Vitamin B9, with the collaboration of vitamin B12 converts homocysteine in methionine therefore reducing blood levels of homocysteine and lowering risks of heart disease.
It also maintains nervous system's integrity and intestinal tract functions. It is involved in the production of neurotransmitters such as serotonin, which regulate mood, sleep and appetite.
Intake
Ages |
micrograms of folic acid per day
|
Infants |
70 |
Children 1-3 years |
100 |
Children 4-6 years |
150 |
Children 7-9 years |
200 |
Children 10-12 years |
250 |
Children 13-15 years |
300 |
Males 16-19 |
330 |
Males 20-50+ |
330 |
Women 16-19 |
300 |
Women 20-50+ |
300 |
Pregnant women |
400 |
Nursing women |
400 |
Deficiency symptoms
A deficiency of folic acid limits cell function (cell division and protein synthesis) and affects the normal growth and repair of all cells and tissues in the body.
The tissues that have the fastest rate of cell replacement are affected first.
Symptoms are:
Good vegetarian sources
It is partially destroyed by cooking and light.
Cautions
Cooking destroys most of the folates contained in vegetables. Even storing at room temperature accelerates the loss of this vitamin.
Keep you vegetables in a dark, cool place and eat them quickly.
High dose of folic acid may mask a vitamin B12 deficiency.
Realized by Laurence LIVERNAIS-SAETTEL, Dietitian.
© Copyright L. Livernais-Saettel 2002
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